Serafini first got his start in Chicago nightlife in the 80’s working for Berlin nightclub as a video jockey and remixer. Under the mentorship of close friends Terri Bristol and Ralphi Rosario, Michael began deejaying regularly in the early 90’s. Shortly after, he took up a position at one of Chicago house’s most famous institutions, Gramaphone Records. As his experience grew, so did his reputation, later landing a residency at Boom Boom Room, then the city’s longest running and well known house night. In 2007, Serafini took over ownership of Gramaphone Records which he still operates today. His current residency is for the weekly Sunday party, Queen! along with Garret David and Derrick Carter.